p75NTR Is Positively Promiscuous Novel Partners and New Insights

نویسنده

  • Philip A Barker
چکیده

Although identified almost 20 years ago, the precise physiological role of the p75 neurotrophin receptor (p75NTR) has remained elusive. Recent studies have revealed that p75NTR is a component of three distinct receptor platforms that bind different ligands and that, under differing circumstances, facilitate cell survival, cell death, or growth inhibition. These recent developments provide new insights into the functions of this enigmatic receptor.

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عنوان ژورنال:
  • Neuron

دوره 42  شماره 

صفحات  -

تاریخ انتشار 2004